HRT may increase joint pain

Women on hormone replacement therpy because of joint aches may experience an increase in pain after stopping treatment warn an expert. This is because estrogen appears to have ubiquitous effects on the female anatomy, where its deficiency may lead to vasomotor and psychosomatic symptoms associated with menopause.

The experts said musculoskeletal aches were common in women of menopausal age and this was reflected in studies conducted in many countries and there is a difference in women of difference cultural backgrounds. Study also said the figture of women complaining of musculoskeletal aches seem to hover around the fifty percent region.

Estrogen replacement in menopause women

A study survey that women on menopausal needs estrogen not just to alleviate vasomotor systoms, but also to prevent a decline in heart and brain health. A professor from university in Australia said doctors and many women perceived hormone replacement as a mean of reducing vasomotor systoms like hot flush and night sweat, But menopause was not merely about these symptoms. He also said that estrogen deficiency had many undersirable effects, the least of which may be vasomotor symptoms.

The doctor also explained that difference parts of the female body had difference forms of estrogen receptors-alphaand beta-receptor. Alpha-receptors mediate faclitatory actions, It was therefore important to understand that although estrogen was mainly thought of as a hormone of the reproductive system, it was a fairly ubiquitous hormone in terms of its effect.

Estrogen attached to the alpha-receptors in the blood vessels, stimulating a cascade of events and mediating the release of nitric oxide, which is a potent dilator of arteries. When the supply was reduced as in menopause, a reduction of blood flow through the arteries ebsued. Estrogen also restores revascularization of arteries adding to its cardiac protection properties.